Sudden infant death syndrome (SIDS) refers to the unexpected, unexplained death of a child less than 1 year old. SIDS is rare during the first month of life. It peaks at 2-4 months of age, then gradually decreases.
Experts do not know the exact cause of SIDS. Many theories exist. Potential causes include:
- Abnormalities in a section of the brain that controls breathing during sleep and waking
- Abnormalities in the control of heart rhythm
- Changes in how serotonin, a neurotransmitter, functions in the brain
- Changes in some components of the immune system
- Inadequate arousal response to breathing obstruction or asphyxia—a lack of oxygen or excess carbon dioxide
Area of the brain involved in regulation of breathing.
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SIDS is more common in infants less than 6 months old. Other factors that increase your infant's chance of SIDS include:
- Low birth weight
- Delayed fetal growth
- History of SIDS death in a sibling
- History of an acute life-threatening event
- Previous incident of unexplained severe apnea—when breathing is repeatedly interrupted and requires resuscitation
- Sleeping on the stomach or side rather than back
- Co-sleeping in parents bed
- Loose covers and blankets
Other risk factors are more general and include:
during pregnancy or in a house where the baby is sleeping
- Alcohol, excessive caffeine, opiate, or
use during pregnancy
- Mother's age—younger than 20 during first pregnancy
- Black, Native American, and Alaskan Native families
- Sex: male
urinary tract infection
- No or late prenatal care
- Premature birth
- Recent infection and/or fever
- Cold weather in late fall or winter
- Low socioeconomic status or low level of education
A baby that dies of SIDS typically appears healthy. The baby may have had a
or gastrointestinal infection in the 2 weeks prior to death. There usually are no warning signs that a baby is about to have SIDS.
All possible illnesses and causes of death must be ruled out before a diagnosis of SIDS is made. A complete investigation will take place including:
- Assessment of the death scene
- Review of the baby and family's medical histories
Emergency medical personnel should be called as soon as the infant is discovered not breathing.
should be started right away. Seek medical care right away even if the baby starts breathing again. The cause of the incident should be fully evaluated. Families may need grief counseling after the death. Some parents find
There is no way to predict which infants will die of SIDS. Several actions may help you lower your child's chance of SIDS:
American Academy of Pediatrics SIDS Task Force. The changing concept of sudden infant death syndrome: diagnostic coding shifts, controversies regarding the sleeping environment, and new variables to consider in reducing risk.
Galland BC, et al. Prone versus supine sleep position: a review of the physiological studies in SIDS research.
J Paediatr Child Health. 2002;38:332-338.
Hunt CE, Hauck FR. Sudden infant death syndrome.
Sudden infant death syndrome (SIDS). EBSCO DynaMed Plus website. Available at:
http://www.dynamed.com/topics/dmp~AN~T113764/Sudden-infant-death-syndrome-SIDS. Updated September 15, 2017. Accessed March 20, 2018.
Sudden infant death syndrome (SIDS). Kid's Health—Nemours Foundation website. Available at:
http://kidshealth.org/parent/general/sleep/sids.html. Updated February 2017. Accessed March 20, 2018.
10/23/2009 DynaMed Plus Systematic Literature Surveillance. http://www.dynamed.com: Blair P, Sidebotham P, et al. Hazardous cosleeping environments and risk factors amenable to change: case-control study of SIDS in south west England. BMJ. 2009;339:b3666.
11/14/2011 DynaMed Plus Systematic Literature Surveillance. http://www.dynamed.com/topics/dmp~AN~T113764/Sudden-infant-death-syndrome-SIDS: Task Force on Sudden Infant Death Syndrome. SIDS and other sleep-related infant deaths: expansion of recommendations for a safe infant sleeping environment. Pediatrics. 2011;128(5):1030-1039.
10/25/2016 DynaMed Plus Systematic Literature Surveillance. http://www.dynamed.com/topics/dmp~AN~T113764/Sudden-infant-death-syndrome-SIDS: SIDS and Other Sleep-Related Infant Deaths: Evidence Base for 2016 Updated Recommendations for a Safe Infant Sleeping Environment Rachel Y. Moon, Task Force on Sudden Infant Death Syndrome. Pediatrics Oct 2016, e20162940; DOI: 10.1542/peds.2016-2940 .
9/26/2017 DynaMed Plus Systematic Literature Surveillance. http://www.dynamed.com/topics/dmp~AN~T113764/Sudden-infant-death-syndrome-SIDS: Psaila K, Foster JP, et al. Infant pacifiers for reduction in risk of sudden infant death syndrome. Cochrane Database Syst Rev. 2017 Apr 5;4:CD011147.
Last reviewed March 2018 by EBSCO Medical Review Board
Kari Kassir, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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